Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL26128657 | 0.99 | HTT (0.43) | HTTHSP90AA1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL22355197 | 0.81 | ATM (0.44) | HSP90AA1ALDH1A1L3MBTL1RECQLKDM4E | |
| Bromide SCHEMBL18555920 | 0.80 | ATM (0.43) | HTTHSP90AA1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL26415049 | 0.76 | KMT2A (0.55) | HSP90AA1ALDH1A1KDM4EPABPC1KMT2A | |
| Bromide SCHEMBL18549649 | 0.74 | KMT2A (0.58) | HSP90AA1ALDH1A1KDM4EPABPC1KMT2A | |
| SCHEMBL12118307 | 0.72 | KMT2A (0.51) | HTTALDH1A1GAARECQLKDM4E | |
| SCHEMBL13865818 | 0.71 | CA4 (0.35) | HTTHSP90AA1CA12CA1CA7 | |
| SCHEMBL25438024 | 0.71 | PABPC1 (0.38) | HTTALDH1A1GAAL3MBTL1KDM4E | |
| Bromide SCHEMBL11490662 | 0.71 | ALDH1A1 (0.44) | HTTHSP90AA1ALDH1A1RECQLKDM4E | |
| Bromide SCHEMBL1312736 | 0.71 | KMT2A (0.54) | HTTALDH1A1GAAL3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183613-A2 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR INFLAMMATION | TACTOGEN INC (US) | 2023-09-28 | — | — | WO | disclosed |