Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23691576 | 0.88 | MAPT (0.42) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL23691258 | 0.86 | MAPT (0.33) | MAPTPOLB | |
| SCHEMBL23663403 | 0.85 | MAPT (0.33) | MAPTL3MBTL1HPGDPOLBMAPK1 | |
| SCHEMBL29965380 | 0.85 | MAPT (0.33) | MAPTL3MBTL1HPGDPOLBMAPK1 | |
| SCHEMBL23691514 | 0.83 | MAPT (0.39) | MAPTL3MBTL1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29965223 | 0.82 | MAPT (0.39) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL23663272 | 0.82 | MAPT (0.39) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL29965239 | 0.77 | P2RX3 (0.34) | MAPTL3MBTL1LMNASMN1; SMN2HPGD | |
| SCHEMBL23663414 | 0.77 | P2RX3 (0.34) | MAPTL3MBTL1LMNASMN1; SMN2HPGD | |
| SCHEMBL23691429 | 0.73 | MAPT (0.45) | MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780825-B2 | Thyroid hormone receptor agonists and use thereof | ECCOGENE (SHANGHAI) CO., LTD. (CN) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780825-B2 | Thyroid hormone receptor agonists and use thereof | TSHR, THRA, THRB | MAPT 112/4885L3MBTL1 4551/4885TDP1 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.