Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019133 | 0.86 | XDH (0.53) | XDHSLC22A12 | |
| SCHEMBL2344031 | 0.86 | XDH (0.53) | XDHSLC22A12 | |
| SCHEMBL7695665 | 0.84 | AAK1 (0.51) | XDHSLC22A12AAK1CYP3A4TLR8 | |
| SCHEMBL7695784 | 0.84 | XDH (0.46) | XDHSLC22A12 | |
| SCHEMBL7695663 | 0.84 | AAK1 (0.51) | XDHSLC22A12AAK1CYP3A4TLR8 | |
| SCHEMBL7695785 | 0.84 | XDH (0.46) | XDHSLC22A12 | |
| SCHEMBL7698039 | 0.80 | XDH (0.41) | XDHSLC22A12AAK1 | |
| SCHEMBL7698040 | 0.80 | XDH (0.41) | XDHSLC22A12AAK1 | |
| SCHEMBL7697256 | 0.80 | HTR1A (0.52) | TLR8 | |
| SCHEMBL7697257 | 0.80 | HTR1A (0.52) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141933-A2 | PROCESS FOR PREPARATION OF 2-[3-CYANO-4-(2-METHYLPROPOXY)PHENYL]-4-METHYLTHIAZOLE-5-CARBOXYLIC ACID AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | MSN LABORATORIES LIMITED (IN) | 2011-11-17 | — | — | WO | disclosed |