Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 7/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | BLVRB | P30043 | 1/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344031 | 1.00 | XDH (0.53) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL2641631 | 0.86 | XDH (0.41) | XDHSLC22A12 | |
| SCHEMBL31573 | 0.85 | XDH (0.69) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL13182575 | 0.83 | XDH (0.53) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL12455378 | 0.83 | MRGPRX4 (0.48) | XDHSLC22A12ABCC4ABCB11PGR | |
| SCHEMBL28291444 | 0.83 | ALDH1A1 (0.45) | XDHSLC22A12 | |
| SCHEMBL6052309 | 0.82 | ALDH1A1 (0.63) | XDHSLC22A12 | |
| SCHEMBL31571 | 0.82 | AAK1 (0.57) | XDHSLC22A12 | |
| SCHEMBL2636175 | 0.82 | ALDH1A1 (0.42) | XDHSLC22A12 | |
| SCHEMBL3746804 | 0.82 | AR (0.50) | XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620829-B | Febuxostat intermediate compound | 鲁南制药集团股份有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-113620832-B | Febuxostat Process for the preparation of intermediates | 鲁南制药集团股份有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-113620829-B | Febuxostat intermediate compound | 鲁南制药集团股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-113620829-B | Febuxostat intermediate compound | 鲁南制药集团股份有限公司 | 2024-05-31 | — | — | CN | disclosed |