SCHEMBL26416601

SCHEMBL26416601

c1ccc(-c2cccc(N(c3ccccc3)c3ccc(-c4cc(-c5nc6ccccc6nc5-c5ccccc5)c5c(c4)oc4ccccc45)cc3)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.34
KDM4E B2RXH2 4/20 0.33
LMNA P02545 4/20 0.33
GAA P10253 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 4/20 0.32
THRB P10828 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HPGD P15428 1/20 0.31
PIK3CA P42336 2/20 0.31
DHODH Q02127 1/20 0.31
PIK3R1 P27986 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
MTOR P42345 1/20 0.31
PIK3CG P48736 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25057649 0.95 L3MBTL1 (0.34) L3MBTL1KDM4ELMNAGAATDP1
SCHEMBL26415503 0.93 L3MBTL1 (0.33) L3MBTL1KDM4ELMNAGAATDP1
SCHEMBL26415506 0.92 L3MBTL1 (0.32) L3MBTL1PLA2G2APLA2G4A
SCHEMBL26416716 0.90 L3MBTL1 (0.38) L3MBTL1KDM4ELMNAGAATDP1
SCHEMBL26415498 0.89 L3MBTL1 (0.31) L3MBTL1KDM4ETDP1MEN1KMT2A
SCHEMBL26415510 0.88 L3MBTL1 (0.33) L3MBTL1KDM4ELMNAGAATDP1
SCHEMBL23385483 0.86 L3MBTL1 (0.40) L3MBTL1KDM4ELMNAGAATDP1
SCHEMBL27391330 0.86 L3MBTL1 (0.38) L3MBTL1KDM4ELMNAGAATDP1
SCHEMBL22112545 0.84 PLA2G2A (0.33) KDM4ELMNAKMT2AALDH1A1HPGD
SCHEMBL26416719 0.84 L3MBTL1 (0.36) L3MBTL1KDM4ELMNAGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128360-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128360-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE CRY1, ORC3, ODC1 L3MBTL1 2788/4885KDM4E 3080/4885LMNA 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.