⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366327 | 0.79 | PI4KA (0.32) | — | |
| SCHEMBL17589204 | 0.78 | — | — | |
| SCHEMBL22942535 | 0.73 | — | — | |
| SCHEMBL12994242 | 0.69 | PI4KA (0.33) | — | |
| SCHEMBL12194508 | 0.67 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL25967747 | 0.67 | MAT2A (0.33) | — | |
| SCHEMBL25768157 | 0.67 | MAT2A (0.31) | — | |
| SCHEMBL15961006 | 0.67 | DRD2 (0.33) | — | |
| SCHEMBL27105319 | 0.66 | GAA (0.31) | — | |
| SCHEMBL16589280 | 0.65 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240217-A1 | NUCLEOSIDES AND NUCLEOTIDES WITH 3' BLOCKING GROUPS AND CLEAVABLE LINKERS | ILLUMINA, INC. | 2024-07-18 | — | — | US | disclosed |
| US-11814450-B2 | Polymeric solid support for oligonucleotide synthesis | HONGENE BIOTECH CORPORATION (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230130509-A1 | POLYMERIC SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | HONGENE BIOTECH CORPORATION | 2023-04-27 | — | — | US | disclosed |