Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12125388 | 0.86 | HPGD (0.67) | HPGDEPHX2NR1H4NPC1ALDH1A1 | |
| SCHEMBL24431446 | 0.81 | HPGD (0.65) | HPGDLMNANPC1ALDH1A1RAB9A | |
| SCHEMBL26417582 | 0.81 | HDAC6 (0.58) | PPARAEPHX2NR1H4NPC1MEN1 | |
| SCHEMBL20665546 | 0.80 | HPGD (0.73) | HPGDLMNATPSAB1HDAC6 | |
| SCHEMBL14995962 | 0.80 | HPGD (0.73) | HPGDLMNANPC1ALDH1A1MEN1 | |
| SCHEMBL3586612 | 0.80 | LMNA (0.65) | HPGDPPARALMNANPC1ALDH1A1 | |
| SCHEMBL17637682 | 0.80 | HPGD (0.58) | HPGDLMNANPC1ALDH1A1MEN1 | |
| SCHEMBL3581796 | 0.80 | PPARA (0.73) | HPGDPPARAEPHX2NPC1ALDH1A1 | |
| SCHEMBL11957489 | 0.79 | L3MBTL1 (0.53) | EPHX2NR1H4NPC1MEN1RAB9A | |
| SCHEMBL15562668 | 0.79 | HPGD (1.00) | HPGDLMNAALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | CD2BP2, CD2, CD47 | HPGD 4378/4885PPARA 4170/4885LMNA 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.