Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581796 | 0.86 | PPARA (0.73) | KMT2AALDH1A1RAB9AHPGDPPARA | |
| SCHEMBL3273904 | 0.81 | LMNA (0.70) | LMNAKMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL20794904 | 0.81 | LMNA (0.65) | LMNAKMT2AALDH1A1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL4026084 | 0.80 | LMNA (0.68) | LMNAKMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL26417587 | 0.80 | HPGD (0.65) | LMNAKMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL3581264 | 0.79 | HTR2C (0.53) | PPARASMN1; SMN2NPC1 | |
| SCHEMBL3578662 | 0.79 | BACE1 (0.56) | LMNAKMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL5601436 | 0.78 | KMT2A (0.62) | LMNAKMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL28992212 | 0.77 | ALDH1A1 (1.00) | LMNAKMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL5861356 | 0.77 | ALDH1A1 (1.00) | LMNAKMT2AALDH1A1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |