Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HBB | P68871 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641844 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2641871 | 0.85 | MAPT (0.39) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2641858 | 0.81 | MAPT (0.55) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2641851 | 0.81 | MAPT (0.55) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL12186023 | 0.79 | PAX8 (0.38) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9000524 | 0.78 | MAPT (0.41) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29905719 | 0.78 | MAPT (0.65) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6498639 | 0.77 | RELA (0.49) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6498636 | 0.77 | RELA (0.49) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL27898404 | 0.76 | MAPT (0.62) | MAPTMEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |