Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | HBB | P68871 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641851 | 1.00 | MAPT (0.55) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL2641830 | 0.85 | BACE1 (0.40) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL1099100 | 0.82 | RAB9A (0.45) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL2641844 | 0.81 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL2641848 | 0.81 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL12749112 | 0.79 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL12185886 | 0.79 | PAX8 (0.39) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL9000484 | 0.78 | MAPT (0.41) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL9799277 | 0.77 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL9799284 | 0.77 | MAPT (0.49) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |