Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24123858 | 0.84 | DRD2 (0.48) | DRD2CYP2D6USP2CYP3A4TSHR | |
| SCHEMBL25675730 | 0.83 | DRD2 (0.47) | DRD2CYP2D6USP2CYP3A4TSHR | |
| SCHEMBL25675717 | 0.82 | DRD2 (0.46) | DRD2CYP2D6USP2CYP3A4TSHR | |
| SCHEMBL25675729 | 0.80 | DRD2 (0.64) | DRD2CYP2D6USP2CYP3A4TSHR | |
| SCHEMBL25678020 | 0.76 | HTR1A (0.48) | DRD2TSHRALDH1A1MAPK1HSD17B10 | |
| SCHEMBL25675701 | 0.76 | NPY2R (0.37) | DRD2CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL24123997 | 0.75 | CYP2D6 (0.63) | DRD2CYP2D6USP2CYP3A4TSHR | |
| SCHEMBL24123588 | 0.74 | HTR1A (0.45) | DRD2TSHRHTR1ADRD4HTR2A | |
| SCHEMBL24123837 | 0.72 | HTR3A (0.40) | DRD2ALDH1A1MEN1KMT2AHTR1A | |
| SCHEMBL25675623 | 0.72 | HTR1A (0.43) | DRD2ALDH1A1HTR1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169919-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |