Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 8/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641876 | 1.00 | KMT2A (0.49) | KMT2ARAB9ANFE2L2APPMAOB | |
| SCHEMBL2641804 | 0.80 | CYP19A1 (0.48) | KMT2ARAB9ANFE2L2APPMAOB | |
| SCHEMBL2641801 | 0.80 | CYP19A1 (0.48) | KMT2ARAB9ANFE2L2APPMAOB | |
| SCHEMBL2943525 | 0.79 | KMT2A (0.52) | KMT2ARAB9ANFE2L2APPMAOB | |
| SCHEMBL1604458 | 0.79 | KMT2A (0.52) | KMT2ARAB9ANFE2L2APPMAOB | |
| SCHEMBL1604461 | 0.79 | KMT2A (0.52) | KMT2ARAB9ANFE2L2APPMAOB | |
| SCHEMBL2943526 | 0.79 | KMT2A (0.52) | KMT2ARAB9ANFE2L2APPMAOB | |
| SCHEMBL2641966 | 0.78 | NFE2L2 (0.40) | NFE2L2APPMAPT | |
| SCHEMBL2641969 | 0.78 | NFE2L2 (0.40) | NFE2L2APPMAPT | |
| SCHEMBL2641766 | 0.76 | APP (0.61) | KMT2ARAB9AAPPMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |