Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641804 | 1.00 | CYP19A1 (0.48) | CYP19A1MAOAMAOBAPPMEN1 | |
| SCHEMBL2641872 | 0.80 | KMT2A (0.49) | CYP19A1MAOAMAOBAPPMEN1 | |
| SCHEMBL2641876 | 0.80 | KMT2A (0.49) | CYP19A1MAOAMAOBAPPMEN1 | |
| SCHEMBL2641969 | 0.78 | NFE2L2 (0.40) | APPMAPTNFE2L2HTR2AKCNH2 | |
| SCHEMBL2641966 | 0.78 | NFE2L2 (0.40) | APPMAPTNFE2L2HTR2AKCNH2 | |
| SCHEMBL2641773 | 0.76 | APP (0.61) | APPMEN1NPC1MAPTRAB9A | |
| SCHEMBL2641811 | 0.76 | APP (0.54) | APPMAPTKCNH2 | |
| SCHEMBL2641766 | 0.76 | APP (0.61) | APPMEN1NPC1MAPTRAB9A | |
| SCHEMBL2641840 | 0.76 | NFE2L2 (0.67) | CYP19A1NPC1MAPTRAB9ANFE2L2 | |
| SCHEMBL2641815 | 0.76 | APP (0.54) | APPMAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |