Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641969 | 1.00 | NFE2L2 (0.40) | NFE2L2KCNH2HTR2AGRM4MAPT | |
| SCHEMBL2641872 | 0.78 | KMT2A (0.49) | NFE2L2MAPTAPP | |
| SCHEMBL2641876 | 0.78 | KMT2A (0.49) | NFE2L2MAPTAPP | |
| SCHEMBL2641804 | 0.78 | CYP19A1 (0.48) | NFE2L2KCNH2HTR2AGRM4MAPT | |
| SCHEMBL2641801 | 0.78 | CYP19A1 (0.48) | NFE2L2KCNH2HTR2AGRM4MAPT | |
| SCHEMBL8619089 | 0.74 | NFE2L2 (0.58) | NFE2L2APP | |
| SCHEMBL2641766 | 0.74 | APP (0.61) | KCNH2MAPTAPP | |
| SCHEMBL2641773 | 0.74 | APP (0.61) | KCNH2MAPTAPP | |
| SCHEMBL115480 | 0.74 | CYP1A1 (0.49) | NFE2L2KCNH2HTR2AMAPT | |
| SCHEMBL2641840 | 0.74 | NFE2L2 (0.67) | NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |