Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641866 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTHTTKMT2ALMNA | |
| SCHEMBL2641834 | 0.84 | HTT (0.42) | ALDH1A1MAPTHTTKMT2ALMNA | |
| SCHEMBL2641809 | 0.80 | KDM4E (0.41) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL2641814 | 0.80 | KDM4E (0.41) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL2641864 | 0.80 | HDAC1 (0.60) | ALDH1A1MAPTKDM4EHDAC1HDAC6 | |
| SCHEMBL2641912 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL2641767 | 0.80 | KDM4E (0.41) | ALDH1A1MAPTKDM4EHDAC1HDAC6 | |
| SCHEMBL2641909 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL2641870 | 0.80 | HDAC1 (0.60) | ALDH1A1MAPTKDM4EHDAC1HDAC6 | |
| SCHEMBL2641775 | 0.80 | KDM4E (0.41) | ALDH1A1MAPTKDM4EHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |