Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641866 | 0.84 | ALDH1A1 (0.42) | HTTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2641874 | 0.84 | ALDH1A1 (0.42) | HTTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2641786 | 0.80 | MAPT (0.43) | HTTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2641779 | 0.80 | MAPT (0.43) | HTTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2641936 | 0.79 | SNCA (0.43) | HTTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2641942 | 0.79 | SNCA (0.43) | HTTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2641924 | 0.78 | HDAC3 (0.41) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2641913 | 0.78 | HDAC3 (0.43) | HTTMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2641827 | 0.78 | HDAC1 (0.44) | MAPTALDH1A1LMNAHDAC3HDAC1 | |
| SCHEMBL2641902 | 0.78 | L3MBTL1 (0.52) | MAPTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |