Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847739 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL11840131 | 0.83 | MAPT (0.43) | KDM4ETSHRALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL261848 | 0.79 | MMP8 (0.44) | KDM4EMMP8TSHRALDH1A1CYP2D6 | |
| SCHEMBL13358859 | 0.77 | MMP8 (0.40) | KDM4EMMP8TSHRALDH1A1CYP2D6 | |
| SCHEMBL12892652 | 0.77 | KDM4E (0.50) | KDM4EMMP8TSHRALDH1A1PIN1 | |
| SCHEMBL13873960 | 0.76 | CYP2D6 (0.43) | ALDH1A1CYP2D6SMN1; SMN2PKMLMNA | |
| SCHEMBL11838855 | 0.76 | CYP1A2 (0.40) | CYP1A2LMNAMAPT | |
| SCHEMBL11780897 | 0.75 | KDM4E (0.57) | KDM4EMMP8TSHRPIN1GAA | |
| SCHEMBL28870213 | 0.75 | KDM4E (0.48) | KDM4EMMP8TSHRALDH1A1PIN1 | |
| SCHEMBL28870216 | 0.75 | KDM4E (0.48) | KDM4EMMP8TSHRALDH1A1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443485-B1 | BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-2443486-B1 | BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2443482-B1 | BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-1781605-B2 | POLYMERS PRODUCED BY USING SULPHUR COMPOUNDS IN THE FORM OF TRANSFER AGENTS FOR CONTROLLED RADICAL POLYMERISATION OF ACRYLIC ACID AND THE USE THEREOF | COATEX SAS (FR) | 2015-04-01 | — | — | EP | disclosed |
| US-8470750-B2 | Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation | COATEX S.A.S (FR) | 2013-06-25 | — | — | US | disclosed |
| US-8470750-B2 | Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation | COATEX S.A.S (FR) | 2013-06-25 | — | — | US | disclosed |
| US-20120259083-A1 | TRITHIOCARBONATE DERIVATIVES AND THE USE THEREOF IN THE FORM OF TRANSFER AGENTS FOR ACRYLIC ACID CONTROLLED RADICAL POLYMERISATION | COATEX S.A.S. (FR) | 2012-10-11 | — | — | US | disclosed |
| US-20120259083-A1 | TRITHIOCARBONATE DERIVATIVES AND THE USE THEREOF IN THE FORM OF TRANSFER AGENTS FOR ACRYLIC ACID CONTROLLED RADICAL POLYMERISATION | COATEX S.A.S. (FR) | 2012-10-11 | — | — | US | disclosed |
| US-8227633-B2 | Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation | COATEX S.A.S. (FR) | 2012-07-24 | — | — | US | disclosed |
| US-8227633-B2 | Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation | COATEX S.A.S. (FR) | 2012-07-24 | — | — | US | disclosed |
| US-20100317816-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317816-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317817-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317817-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-7851572-B2 | Polymers produced by using sulphur compounds in the form of transfer agents for controlled radical polymerisation of acrylic acid and the use thereof | COATEX S.A.S. (FR) | 2010-12-14 | — | — | US | disclosed |
| US-7851572-B2 | Polymers produced by using sulphur compounds in the form of transfer agents for controlled radical polymerisation of acrylic acid and the use thereof | COATEX S.A.S. (FR) | 2010-12-14 | — | — | US | disclosed |
| US-20070197747-A1 | Polymers Produced By Using Sulphur Compounds In The Form Of Transfer Agents For Controlled Radical Polymerisation Of Acrylic Acid And The Use Thereof | COATEX S.A.S. (FR) | 2007-08-23 | — | — | US | disclosed |
| US-20070197747-A1 | Polymers Produced By Using Sulphur Compounds In The Form Of Transfer Agents For Controlled Radical Polymerisation Of Acrylic Acid And The Use Thereof | COATEX S.A.S. (FR) | 2007-08-23 | — | — | US | disclosed |
| US-20070179262-A1 | Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation | COATEX S.A.S. (FR) | 2007-08-02 | — | — | US | disclosed |
| US-20070179262-A1 | Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation | COATEX S.A.S. (FR) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179262-A1 | Trithiocarbonate derivatives and the use thereof in the form of transfer agents for acrylic acid controlled radical polymerisation | TST, AS3MT, TTPA | KDM4E 4504/4885MMP8 4570/4885TSHR 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.