Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 5/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641882 | 1.00 | RELA (0.54) | RELANFE2L2CYP1A2KDM4ENPC1 | |
| SCHEMBL2641781 | 0.78 | APP (0.54) | RELANPC1RAB9ASMN1; SMN2SNCA | |
| SCHEMBL2641774 | 0.78 | APP (0.54) | RELANPC1RAB9ASMN1; SMN2SNCA | |
| SCHEMBL631997 | 0.77 | TRPA1 (0.76) | RELANFE2L2CYP1A2KDM4ENPC1 | |
| SCHEMBL631996 | 0.77 | TRPA1 (0.76) | RELANFE2L2CYP1A2KDM4ENPC1 | |
| SCHEMBL16597820 | 0.76 | KDM4E (0.63) | RELANFE2L2CYP1A2KDM4ENPC1 | |
| SCHEMBL16597578 | 0.76 | KDM4E (0.63) | RELANFE2L2CYP1A2KDM4ENPC1 | |
| SCHEMBL1157127 | 0.75 | TRIM24 (0.53) | NFE2L2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL1157125 | 0.75 | TRIM24 (0.53) | NFE2L2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL8602997 | 0.75 | MAPT (0.62) | RELACYP1A2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |