Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641983 | 0.84 | GABRA1 (0.55) | HPGDALDH1A1FGFR1GABRA1GABRG2 | |
| SCHEMBL2641981 | 0.83 | FGFR1 (0.56) | HPGDALDH1A1FGFR1GABRA1GABRG2 | |
| Hydrochloric Acid SCHEMBL2641992 | 0.82 | FGFR1 (0.54) | HPGDALDH1A1FGFR1GABRA1GABRG2 | |
| SCHEMBL1762010 | 0.81 | GABRA1 (0.52) | HPGDALDH1A1FGFR1GABRA1GABRG2 | |
| SCHEMBL1761954 | 0.80 | GABRA1 (0.57) | HPGDALDH1A1FGFR1GABRA1GABRG2 | |
| SCHEMBL6834170 | 0.79 | MTOR (0.46) | HPGDALDH1A1FGFR1GABRA1GABRG2 | |
| SCHEMBL1762032 | 0.78 | GABRA1 (0.60) | HPGDALDH1A1FGFR1GABRA1GABRG2 | |
| SCHEMBL31606903 | 0.77 | ADORA2A (0.51) | XDH | |
| SCHEMBL19915930 | 0.77 | FGFR1 (0.62) | ALDH1A1FGFR1KDR | |
| SCHEMBL2646769 | 0.76 | HTT (0.59) | HPGDALDH1A1FGFR1AURKAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | claimed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | claimed |
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |