Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | F9 | P00740 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2641992 | 0.99 | FGFR1 (0.54) | FGFR1ALDH1A1HPGDGABRA1GABRG2 | |
| SCHEMBL6834170 | 0.86 | MTOR (0.46) | FGFR1ALDH1A1HPGDGABRA1GABRG2 | |
| SCHEMBL2641983 | 0.85 | GABRA1 (0.55) | FGFR1ALDH1A1HPGDGABRA1GABRG2 | |
| SCHEMBL2641906 | 0.83 | HPGD (0.45) | FGFR1ALDH1A1HPGDGABRA1GABRG2 | |
| SCHEMBL2642002 | 0.82 | HPGD (0.46) | FGFR1ALDH1A1HPGDGABRA1GABRG2 | |
| SCHEMBL29623727 | 0.82 | FGFR1 (0.59) | FGFR1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL19350767 | 0.82 | FGFR1 (0.59) | FGFR1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL19915930 | 0.81 | FGFR1 (0.62) | FGFR1ALDH1A1KDR | |
| SCHEMBL2646769 | 0.81 | HTT (0.59) | FGFR1ALDH1A1HPGDKDRAURKA | |
| Hydrochloric Acid SCHEMBL2642036 | 0.81 | GABRA1 (0.46) | FGFR1ALDH1A1HPGDGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | claimed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | claimed |
| JP-6049037-A | — | — | None | — | — | JP | disclosed |
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| JP-H0649037-A | IMIDAZOLE COMPOUND, PRODUCTION AND USE THEREOF | NEUROSEARCH AS | 1994-02-22 | — | — | JP | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |