Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854117 | 0.69 | LMNA (0.37) | PDE2APDE1APDE1BPDE1C | |
| SCHEMBL26420407 | 0.67 | TGFBR1 (0.37) | — | |
| SCHEMBL18405893 | 0.62 | LMNA (0.38) | PDE2APDE1APDE1BPDE1C | |
| SCHEMBL24854116 | 0.61 | LMNA (0.40) | — | |
| SCHEMBL22380086 | 0.60 | ALDH1A1 (0.40) | PDE2APDE1APDE1BPDE1C | |
| SCHEMBL18663600 | 0.60 | LMNA (0.38) | — | |
| SCHEMBL24854962 | 0.59 | ALDH1A1 (0.33) | — | |
| SCHEMBL26419086 | 0.58 | CSNK2A2 (0.44) | — | |
| SCHEMBL16883535 | 0.58 | DAO (0.45) | — | |
| SCHEMBL17307154 | 0.57 | DPP4 (0.40) | PDE2APDE1APDE1BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128824-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128824-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | KRAS, NRAS, HRAS | PDE2A 2596/4885PDE1A 1086/4885PDE1B 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.