SCHEMBL2642250

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2659886	0.86	GCK (0.40)	HTTGCKALDH1A1LMNACYP1A2
	SCHEMBL2642649	0.86	GCK (0.42)	GCKEGFRKDRABCG2PIK3CA
	SCHEMBL2642043	0.84	GCK (0.40)	HTTGCKEGFRALDH1A1LMNA
	SCHEMBL2642210	0.83	GCK (0.46)	HTTGCKEGFRLMNACYP1A2
	SCHEMBL2660952	0.83	PKM (0.40)	HTTGCKEGFRALDH1A1LMNA
	SCHEMBL2642489	0.83	GCK (0.43)	HTTGCKEGFRALDH1A1LMNA
	SCHEMBL2646674	0.82	GCK (0.39)	GCKEGFRLMNACYP1A2CYP3A4
	SCHEMBL2642164	0.79	GCK (0.42)	HTTGCKEGFRKDRMEN1
	SCHEMBL2642200	0.79	GCK (0.53)	GCKEGFRMEN1NPC1KMT2A
	SCHEMBL2642648	0.79	GCK (0.42)	HTTGCKEGFRLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.