SCHEMBL2642649

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2642164	0.89	GCK (0.42)	GCKNPC1RAB9ASMN1; SMN2CD38
	SCHEMBL2642250	0.86	HTT (0.43)	GCKNPC1EGFRPIK3CAKDR
	SCHEMBL2642043	0.86	GCK (0.40)	GCKNPC1RAB9ASMN1; SMN2CD38
	SCHEMBL2642210	0.86	GCK (0.46)	GCKNPC1RAB9ASMN1; SMN2CD38
	SCHEMBL2660952	0.85	PKM (0.40)	GCKNPC1RAB9ASMN1; SMN2POLB
	SCHEMBL2642489	0.85	GCK (0.43)	GCKNPC1RAB9ASMN1; SMN2CD38
	SCHEMBL2646674	0.84	GCK (0.39)	GCKNPC1RAB9ASMN1; SMN2CD38
	SCHEMBL2659886	0.83	GCK (0.40)	GCKNPC1RAB9ASMN1; SMN2POLB
	SCHEMBL2642648	0.81	GCK (0.42)	GCKNPC1RAB9ASMN1; SMN2CD38
	SCHEMBL2642607	0.79	GCK (0.44)	GCKNPC1RAB9ASMN1; SMN2CD38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.