SCHEMBL26424764

SCHEMBL26424764

NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)CCC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MME P08473 14/20 0.60
MMEL1 Q495T6 5/20 0.53
ACE P12821 2/20 0.50
KMT2A Q03164 1/20 0.45
PTPN1 P18031 2/20 0.45
PTPN2 P17706 1/20 0.45
PTPRA P18433 1/20 0.45
PTPN6 P29350 1/20 0.45
PTPN11 Q06124 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26426151 0.87 MME (0.45) MMEMMEL1ACEKMT2APTPN1
SCHEMBL26425109 0.87 MME (0.56) MMEACE
SCHEMBL26424799 0.86 MMEL1 (0.47) MMEMMEL1ACE
SCHEMBL26424706 0.85 KMT2A (0.56) MMEMMEL1ACEKMT2A
SCHEMBL18262572 0.83 CA2 (0.49) MMEKMT2A
SCHEMBL18262574 0.83 CA2 (0.49) MMEKMT2A
SCHEMBL29511612 0.83 KMT2A (0.54) MMEMMEL1ACEKMT2A
SCHEMBL26424830 0.82 MMEL1 (0.46) MMEMMEL1ACE
SCHEMBL26426392 0.80 FCER2 (0.58) MMEACE
SCHEMBL15617940 0.78 KMT2A (0.55) MMEACEKMT2APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
EP-4170347-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2023-04-26 EP disclosed