SCHEMBL26426151

SCHEMBL26426151

NC(=O)[C@H](Cc1cc(Cl)cc(Cl)c1)NC(=O)CCC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MME P08473 11/20 0.45
MMEL1 Q495T6 4/20 0.45
ACE P12821 1/20 0.43
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 1/20 0.42
GNPAT O15228 1/20 0.40
PARP1 P09874 1/20 0.40
PARP3 Q9Y6F1 1/20 0.40
PTPN1 P18031 2/20 0.38
PTPN2 P17706 1/20 0.38
PTPRA P18433 1/20 0.38
PTPN6 P29350 1/20 0.38
PTPN11 Q06124 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP10 P09238 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP12 P39900 1/20 0.38
MMP13 P45452 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26424764 0.87 MME (0.60) MMEMMEL1ACEKMT2APTPN1
SCHEMBL26424706 0.86 KMT2A (0.56) MMEMMEL1ACEALDH1A1KMT2A
SCHEMBL26425109 0.82 MME (0.56) MMEACEPARP1PARP3
SCHEMBL26424799 0.82 MMEL1 (0.47) MMEMMEL1ACE
SCHEMBL26424830 0.78 MMEL1 (0.46) MMEMMEL1ACEALDH1A1
SCHEMBL26426129 0.76 MME (0.46) MMEMMEL1ACEMMP2MMP8
SCHEMBL26426392 0.75 FCER2 (0.58) MMEACEPARP1PARP3MMP3
SCHEMBL26425140 0.74 CTSG (0.52) MMEMMEL1ACEKMT2AMMP2
SCHEMBL22241539 0.72 GNPAT (0.50) MMEGNPATMMP2MMP8MMP12
SCHEMBL17513378 0.71 TACR1 (0.56) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
EP-4170347-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2023-04-26 EP disclosed