Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.47 |
| ▸ | HTR3B | O95264 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473210 | 0.80 | HTR3E (0.52) | PNMTIDO1TAAR1HTR3EHTR3B | |
| SCHEMBL3084924 | 0.79 | PNMT (0.54) | PNMTIDO1TAAR1HTR3EHTR3B | |
| SCHEMBL167780 | 0.77 | PNMT (0.56) | PNMTIDO1TAAR1HTR3EHTR3B | |
| SCHEMBL19433071 | 0.76 | MAOB (0.52) | IDO1CYP3A4ALDH1A1TSHR | |
| SCHEMBL15702910 | 0.76 | MAOB (0.52) | IDO1CYP3A4ALDH1A1TSHR | |
| SCHEMBL9131503 | 0.76 | PNMT (0.55) | PNMTIDO1TAAR1HTR3EHTR3B | |
| SCHEMBL6083088 | 0.75 | HTR3E (0.55) | PNMTIDO1TAAR1HTR3EHTR3B | |
| SCHEMBL28879871 | 0.75 | PNMT (0.54) | PNMTIDO1TAAR1HTR3EHTR3B | |
| SCHEMBL771274 | 0.75 | PNMT (0.54) | PNMTIDO1TAAR1HTR3EHTR3B | |
| SCHEMBL7481246 | 0.75 | PNMT (0.59) | PNMTIDO1TAAR1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069721-A2 | OXAZOLE, OXADIAZOLE, AND INDOLE DERIVATIVES FOR THE INHIBITION OF USP28 | CARMOT THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |