Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.52 |
| ▸ | HTR3B | O95264 | 3/20 | 0.52 |
| ▸ | HTR3A | P46098 | 3/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.51 |
| ▸ | PNMT | P11086 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26425581 | 0.80 | PNMT (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3714059 | 0.80 | ENPP2 (0.50) | TAAR1CTBP2CYP3A4ALDH1A1LMNA | |
| SCHEMBL27784818 | 0.80 | HTR3E (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6083088 | 0.79 | HTR3E (0.55) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8661359 | 0.79 | TSHR (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28353912 | 0.78 | TAAR1 (0.50) | IDO1TAAR1CTBP2NPC1 | |
| SCHEMBL10991036 | 0.78 | HTR3E (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10991040 | 0.78 | HTR3E (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL17276661 | 0.78 | TAAR1 (0.46) | IDO1TAAR1CYP3A4AGXTSMN1; SMN2 | |
| SCHEMBL4083760 | 0.78 | PNMT (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511742-A1 | KINASE INHIBITORS | Cytopia PTY Ltd (AU) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003099811-A1 | KINASE INHIBITORS | CYTOPIA PTY LTD (AU) | 2003-12-04 | — | — | WO | disclosed |