Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 3/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26427476 | 1.00 | KDM4E (0.39) | KDM4EPKMGPR119HPGDSUSP30 | |
| SCHEMBL26427522 | 0.82 | KDM4E (0.40) | KDM4EPKMGPR119HPGDSUSP30 | |
| SCHEMBL26427495 | 0.81 | KDM4E (0.39) | KDM4EPKMGPR119HPGDSUSP30 | |
| SCHEMBL26427466 | 0.79 | MAPK1 (0.43) | KDM4EPKMGPR119HPGDSUSP30 | |
| SCHEMBL30419474 | 0.78 | HTR2C (0.54) | HTR2CMEN1KMT2AMAPK1 | |
| SCHEMBL30419044 | 0.78 | HTR2C (0.54) | HTR2CMEN1KMT2AMAPK1 | |
| SCHEMBL26427463 | 0.74 | MAPK1 (0.40) | KDM4EPKMGPR119USP30RORC | |
| SCHEMBL26427489 | 0.71 | MEN1 (0.42) | KDM4EPKMGPR119HPGDSUSP30 | |
| SCHEMBL27952715 | 0.71 | SMARCA2 (0.48) | KDM4EPKMGPR119USP30MEN1 | |
| SCHEMBL17858779 | 0.71 | GAA (0.51) | KDM4EPKMGPR119HPGDSUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067353-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |