SCHEMBL30419474

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30419044	1.00	HTR2C (0.54)	HTR2CPDK1PDK2PDK3PDK4
	SCHEMBL38665508	0.85	PDK1 (0.49)	HTR2CPDK1PDK2PDK3PDK4
	SCHEMBL30419035	0.85	PDK1 (0.49)	HTR2CPDK1PDK2PDK3PDK4
	SCHEMBL38666171	0.83	HTR2C (0.42)	HTR2CPDK1PDK2PDK3PDK4
	SCHEMBL30419634	0.82	HTR2C (0.48)	HTR2CPDK1PDK2PDK3PDK4
	SCHEMBL26093708	0.80	MEN1 (0.45)	HTR2CMEN1KMT2AHTTPARP1
	SCHEMBL38665121	0.78	HTR2C (0.54)	HTR2CPDK1PDK2PDK3PDK4
	SCHEMBL26427476	0.78	KDM4E (0.39)	HTR2CMEN1KMT2AMAPK1
	SCHEMBL26427482	0.78	KDM4E (0.39)	HTR2CMEN1KMT2AMAPK1
	SCHEMBL26090531	0.76	NPC1 (0.43)	HTR2CMEN1KMT2AHTTPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.