SCHEMBL26428853

SCHEMBL26428853

CCC(=O)NCc1cc(F)c(OC(=O)C(C)C)c(F)c1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.39
S1PR3 Q99500 1/20 0.36
CARM1 Q86X55 1/20 0.36
PRMT6 Q96LA8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26418208 0.87 ERCC1 (0.47) HPGDS1PR3CARM1PRMT6
SCHEMBL26422825 0.79 ERCC1 (0.44) HPGDS1PR3CARM1PRMT6
SCHEMBL26417663 0.77 ALOX15 (0.40)
SCHEMBL23417836 0.75 ERCC1 (0.47) HPGDS1PR3CARM1PRMT6
SCHEMBL17662449 0.74 ELANE (0.40)
SCHEMBL26428984 0.74 ADRB2 (0.38)
SCHEMBL26422908 0.73 TOP2A (0.41) HPGD
SCHEMBL1456923 0.72 P2RX7 (0.49) HPGD
SCHEMBL1456919 0.72 P2RX7 (0.49) HPGD
SCHEMBL31036978 0.72 P2RX7 (0.49) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES KLEO PHARMACEUTICALS, INC. 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES CD2BP2, CD2, CD47 HPGD 4378/4885S1PR3 2576/4885CARM1 802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.