Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 3/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | PAK4 | O96013 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | LTK | P29376 | 1/20 | 0.49 |
| ▸ | GRK5 | P34947 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302596 | 0.81 | SMN1; SMN2 (0.63) | APPSMN1; SMN2MAP4K4GPR68ADORA2A | |
| SCHEMBL10483507 | 0.75 | MEN1 (0.57) | SMN1; SMN2CLK4KDM4C | |
| SCHEMBL17741901 | 0.75 | APP (0.56) | APPPAK4RPS6KB1CCNT1ADORA3 | |
| SCHEMBL4385162 | 0.74 | NTRK1 (0.49) | APPJAK2PAK4JAK3PRKCQ | |
| SCHEMBL17220381 | 0.72 | APP (0.50) | APPSMN1; SMN2HRH4CCNT1GPR68 | |
| SCHEMBL22191429 | 0.72 | GAA (0.52) | APPAURKAAURKBDAPK3JAK2 | |
| SCHEMBL5153294 | 0.71 | HRH4 (0.57) | APPSMN1; SMN2HRH4CCNT1KDM5A | |
| SCHEMBL15452392 | 0.71 | BCL6 (0.54) | APPSMN1; SMN2HRH4ADORA3ADORA2A | |
| SCHEMBL25934296 | 0.71 | GAA (0.51) | APPSMN1; SMN2AURKAAURKBDAPK3 | |
| SCHEMBL18276309 | 0.71 | VCP (0.45) | APPSMN1; SMN2AURKAAURKBDAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | CD2BP2, CD2, CD47 | APP 4235/4885SMN1; SMN2 1694/4885AURKA 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.