Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.44 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 10/20 | 0.39 |
| ▸ | CTSD | P07339 | 3/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29577402 | 0.83 | FURIN (0.52) | FURINPCSK6 | |
| SCHEMBL3035812 | 0.83 | FURIN (0.52) | FURINPCSK6 | |
| SCHEMBL16566020 | 0.81 | DPP8 (0.42) | OPRK1DPP8DPP9DPP7 | |
| SCHEMBL29387347 | 0.81 | BACE1 (0.51) | FURINPCSK6BACE1CTSDBACE2 | |
| SCHEMBL30629771 | 0.80 | NPY4R (0.45) | FURINPCSK6BACE1CTSDBACE2 | |
| SCHEMBL29384387 | 0.80 | NTSR2 (0.45) | FURINPCSK6BACE1CTSDBACE2 | |
| SCHEMBL29531524 | 0.80 | NTSR2 (0.45) | FURINPCSK6BACE1CTSDBACE2 | |
| SCHEMBL10381547 | 0.79 | FURIN (0.48) | FURINPCSK6BACE1CTSDBACE2 | |
| SCHEMBL10381550 | 0.79 | FURIN (0.48) | FURINPCSK6BACE1CTSDBACE2 | |
| SCHEMBL29368320 | 0.79 | BACE1 (0.51) | BACE1CTSDBACE2NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127524-A1 | FILAMENTOUS NANOSTRUCTURES AND THEIR USE FOR TREATMENT OF PULMONARY DISEASE | NATIONAL SCIENCE FOUNDATION | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127524-A1 | FILAMENTOUS NANOSTRUCTURES AND THEIR USE FOR TREATMENT OF PULMONARY DISEASE | MFAP1, DIAPH1, SEPTIN7 | FURIN 1779/4885PCSK6 2801/4885BACE1 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.