SCHEMBL26431886

SCHEMBL26431886

c1ccc(-c2nc(-c3ccc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)c4ccccc34)cc(-c3cc4ccccc4c4ccccc34)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ ATM Q13315 1/20 0.41
▸ CYP11B1 P15538 1/20 0.36
▸ KMT2A Q03164 5/20 0.35
▸ MAPT P10636 5/20 0.35
▸ MEN1 O00255 4/20 0.35
▸ ALDH1A1 P00352 4/20 0.35
▸ HPGD P15428 4/20 0.35
▸ NTSR1 P30989 1/20 0.35
▸ MAPK1 P28482 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ HDAC4 P56524 1/20 0.33
▸ RXRA P19793 1/20 0.33
▸ LMNA P02545 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ MPI P34949 1/20 0.33
▸ PTK2B Q14289 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12210999 0.93 KMT2A (0.43) KDM4EL3MBTL1ATMCYP11B1KMT2A
SCHEMBL25680007 0.92 KDM4E (0.47) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL12211010 0.92 KDM4E (0.43) KDM4EL3MBTL1ATMCYP11B1KMT2A
SCHEMBL24752687 0.92 L3MBTL1 (0.39) KDM4EL3MBTL1ATMCYP11B1KMT2A
SCHEMBL14416347 0.91 KMT2A (0.42) KDM4EL3MBTL1ATMCYP11B1KMT2A
SCHEMBL17899170 0.90 KMT2A (0.43) KDM4EL3MBTL1ATMCYP11B1KMT2A
SCHEMBL13100588 0.90 KMT2A (0.45) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL24752103 0.89 KDM4E (0.40) KDM4EL3MBTL1ATMCYP11B1KMT2A
SCHEMBL14416366 0.89 KDM4E (0.41) KDM4EL3MBTL1ATMKMT2AMAPT
SCHEMBL12211002 0.89 TUBB4A (0.41) KDM4EL3MBTL1ATMCYP11B1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-04-27 — — US disclosed
US-20230127629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127629-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, EPCAM, TMEM109 KDM4E 3098/4885L3MBTL1 1434/4885ATM 2552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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