Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461486 | 0.76 | PDE3B (0.61) | PDE2APDE3BPDE3AKMT2A | |
| SCHEMBL7280920 | 0.76 | PDE3B (1.00) | PDE2APDE3BPDE3AHTTMGAM | |
| SCHEMBL10755622 | 0.75 | PDE3B (0.62) | PDE2APDE3BPDE3AMGAMGAA | |
| Hydrochloric Acid SCHEMBL10759777 | 0.74 | PDE3B (0.60) | PDE2APDE3BPDE3AMGAMGAA | |
| SCHEMBL2531256 | 0.74 | HTT (0.78) | PDE2APDE3BPDE3AHTTFGFR1 | |
| SCHEMBL6281045 | 0.73 | HTT (0.66) | HTTFGFR1KDM4EALDH1A1RAB9A | |
| SCHEMBL31521527 | 0.73 | CRBN (0.58) | PDE2APDE3BPDE3AHTTMGAM | |
| SCHEMBL11008299 | 0.73 | SRD5A1 (0.42) | PDE3BPDE3AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30402227 | 0.72 | HTT (0.88) | HTTFGFR1KDM4EALDH1A1RAB9A | |
| SCHEMBL3419279 | 0.72 | HTT (0.88) | HTTFGFR1KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |