Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962552 | 0.91 | CA12 (0.54) | CA12CA1CA2CA9MAPT | |
| SCHEMBL2286201 | 0.89 | CA12 (0.53) | CA12CA1CA2CA9MAPT | |
| SCHEMBL2286199 | 0.89 | CA12 (0.53) | CA12CA1CA2CA9MAPT | |
| SCHEMBL13989319 | 0.89 | GAA (0.73) | CA12CA1CA2CA9MAPT | |
| SCHEMBL1709756 | 0.84 | TP53 (0.72) | CA12CA1CA2CA9MAPT | |
| SCHEMBL15197080 | 0.83 | MAPT (0.64) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8751494 | 0.82 | CA1 (0.64) | CA1CA2MAPTSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL8531055 | 0.82 | CA12 (0.61) | CA12CA1CA2CA9MAPT | |
| SCHEMBL11193707 | 0.81 | CA12 (0.56) | CA12CA1CA2CA9MAPT | |
| SCHEMBL10360235 | 0.81 | CA1 (0.67) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198796-B1 | MONOAZO DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | claimed |
| US-4866164-A | MONOAZO DYES FOR NATURAL AND SYNTHETIC POLYAMIDES; LIGHTFASTNESS, WETFASTNESS | CIBA-GEIGY CORPORATION (US) | 1989-09-12 | — | — | US | claimed |
| CN-86105641-A | The method for preparing antianaphylaxis and antibronchospasm of N-dibenzyl-diazacyclo alkyl-alkyl-anilide | — | 1987-04-01 | — | — | CN | claimed |
| EP-0198796-A2 | Monoazo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1986-10-22 | — | — | EP | claimed |
| US-4487610-A | Cold water soluble anthraquinone dyestuff composition | CIBA-GEIGY CORPORATION (US) | 1984-12-11 | — | — | US | claimed |
| CN-113527133-B | Amine antioxidant and preparation method and application thereof | 中国石油天然气股份有限公司 | 2023-09-26 | — | — | CN | disclosed |
| WO-2023078273-A1 | SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |
| CN-108530444-B | Novel NAMPT and IDO dual inhibitor and preparation method and medical application thereof | 药康众拓(江苏)医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-107635553-B | Pyrimidine derivatives as kinase inhibitors and their therapeutic use | 常山凯捷健生物药物研发（河北）有限公司 | 2020-08-14 | — | — | CN | disclosed |
| EP-3261638-B1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS AND THEIR THERAPEUTICAL APPLICATIONS | NANTBIOSCIENCE INC (US) | 2019-05-08 | — | — | EP | disclosed |
| CN-108530444-A | A kind of novel NAMPT and IDO double inhibitors and preparation method thereof and medical usage | 中国药科大学 | 2018-09-14 | — | — | CN | disclosed |
| US-20180215734-A1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS AND THEIR THERAPEUTICAL APPLICATIONS | NANTBIOSCIENCE, INC. | 2018-08-02 | — | — | US | disclosed |
| US-4137228-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-4132799-A | TRANQUILIZERS, ANTICONVULSANTS | MERCK & CO., INC. (US) | 1979-01-02 | — | — | US | disclosed |
| US-4091025-A | AMINATION, NITRATION, SAPONIFICATION | CIBA-GEIGY AG (CH) | 1978-05-23 | — | — | US | disclosed |
| US-4080321-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
| US-4061763-A | TRANQUILIZER, ANTICONVULSANT | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4006233-A | TRANQUILIZER, ANTICONVULSANT | MERCK & CO., INC. (US) | 1977-02-01 | — | — | US | disclosed |
| US-3992421-A | ANTHRAQUINONE DYESTUFFS FOR BLUE DYEINGS OF POLYESTERS | AMERICAN COLOR & CHEMICAL CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3971741-A | DISPERSION PIGMENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215734-A1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS AND THEIR THERAPEUTICAL APPLICATIONS | DCK, TK1, DTYMK | CA12 4879/4885CA1 4871/4885CA2 4405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.