SCHEMBL26433934

SCHEMBL26433934

CCCCC1(C)CC(C)(C)c2cc3c(cc21)nc1c2ccccc2nc(C(C)(C)C)n31

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
HPGD P15428 4/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 2/20 0.33
POLB P06746 2/20 0.33
TP53 P04637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ADORA3 P0DMS8 7/20 0.32
ADORA1 P30542 1/20 0.32
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
RXRA P19793 2/20 0.31
PSMD14 O00487 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15428183 0.87 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL15428261 0.83 KDM4E (0.40) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL15427826 0.81 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL19669299 0.79 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL15427828 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL15428226 0.78 KDM4E (0.36) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL15428271 0.77 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL19670893 0.77 KDM4E (0.38) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL19669293 0.76 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL15428256 0.76 L3MBTL1 (0.33) ALDH1A1KDM4EHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4069663-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-12-13 EP disclosed
EP-3512841-B1 COMPOUNDS WITH SPIROBIFLUORENE-STRUCTURES MERCK PATENT GMBH (DE) 2023-04-26 EP disclosed