Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.54 |
| ▸ | IL1B | P01584 | 11/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26435057 | 0.92 | NLRP3 (0.49) | NLRP3IL1BALDH1A1TNFKDM4E | |
| SCHEMBL26436144 | 0.90 | IL1B (0.59) | NLRP3IL1BTNF | |
| SCHEMBL26436158 | 0.89 | NLRP3 (0.46) | NLRP3IL1BTNF | |
| SCHEMBL26435329 | 0.89 | NLRP3 (0.44) | NLRP3IL1BTNF | |
| SCHEMBL26435083 | 0.89 | NLRP3 (0.56) | NLRP3IL1BALDH1A1KDM4EHSD17B10 | |
| SCHEMBL26434881 | 0.85 | IL1B (0.49) | NLRP3IL1BALDH1A1TNFKDM4E | |
| SCHEMBL24840758 | 0.85 | NLRP3 (0.73) | NLRP3IL1BALDH1A1 | |
| SCHEMBL26434876 | 0.85 | NLRP3 (0.73) | NLRP3IL1BALDH1A1 | |
| SCHEMBL30168047 | 0.85 | NLRP3 (0.73) | NLRP3IL1BALDH1A1 | |
| SCHEMBL26435307 | 0.83 | NLRP3 (0.47) | NLRP3IL1BALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |