SCHEMBL26435236

SCHEMBL26435236

c1ccc(-c2cccc(-c3ccc(-c4nc(-c5ccc6oc7ccccc7c6c5)nc(-c5cccc6ccc7ccccc7c56)n4)cc3)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.40
PLA2G4A P47712 3/20 0.40
PLA2G10 O15496 1/20 0.40
KDM4E B2RXH2 4/20 0.40
MAPT P10636 4/20 0.40
HPGD P15428 3/20 0.40
TSHR P16473 3/20 0.40
HSD17B10 Q99714 3/20 0.40
ALDH1A1 P00352 3/20 0.40
ALOX15 P16050 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
ABCG2 Q9UNQ0 6/20 0.40
AHR P35869 2/20 0.40
CYP1A1 P04798 1/20 0.40
CYP1A2 P05177 1/20 0.40
FYN P06241 1/20 0.40
MAPK3 P27361 1/20 0.40
PAX8 Q06710 1/20 0.40
MAPK1 P28482 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26435221 0.98 ABCG2 (0.41) PLA2G2APLA2G4APLA2G10KDM4EMAPT
SCHEMBL26435234 0.98 ABCG2 (0.41) PLA2G2APLA2G4APLA2G10KDM4EMAPT
SCHEMBL26435218 0.96 ABCG2 (0.42) PLA2G2APLA2G4APLA2G10KDM4EMAPT
SCHEMBL26435233 0.95 KDM4E (0.40) PLA2G2APLA2G4APLA2G10KDM4EMAPT
SCHEMBL26435469 0.94 ABCG2 (0.40) PLA2G2APLA2G4APLA2G10KDM4EMAPT
SCHEMBL21741728 0.93 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10KDM4EMAPT
SCHEMBL26435211 0.93 ALDH1A1 (0.39) PLA2G2APLA2G4APLA2G10KDM4EMAPT
SCHEMBL26435226 0.93 MAPT (0.38) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL23759418 0.93 ABCG2 (0.41) PLA2G2APLA2G4APLA2G10KDM4EMAPT
SCHEMBL23759470 0.93 ABCG2 (0.41) PLA2G2APLA2G4APLA2G10KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320205-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 PLA2G2A 4314/4885PLA2G4A 4445/4885PLA2G10 3828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.