Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 16/20 | 0.35 |
| ▸ | KLK1 | P06870 | 12/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407282 | 1.00 | F11 (0.35) | F11KLK1DDB1CRBNPOLB | |
| SCHEMBL26435068 | 0.93 | DDB1 (0.39) | F11KLK1DDB1CRBNPOLB | |
| SCHEMBL31115915 | 0.89 | EPHX2 (0.38) | F11KLK1DDB1CRBNPOLB | |
| SCHEMBL26435246 | 0.89 | EPHX2 (0.38) | F11KLK1DDB1CRBNPOLB | |
| SCHEMBL26089970 | 0.87 | FPR1 (0.39) | F11KLK1DDB1CRBNPOLB | |
| SCHEMBL30407787 | 0.87 | FPR1 (0.39) | F11KLK1DDB1CRBNPOLB | |
| SCHEMBL30407993 | 0.86 | DDB1 (0.40) | DDB1CRBNGSPT1 | |
| SCHEMBL26436839 | 0.86 | DDB1 (0.40) | DDB1CRBNGSPT1 | |
| SCHEMBL30349632 | 0.86 | DDB1 (0.36) | F11KLK1DDB1CRBNPOLB | |
| SCHEMBL26090625 | 0.86 | DDB1 (0.36) | F11KLK1DDB1CRBNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |