Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 5/20 | 0.35 |
| ▸ | KLK1 | P06870 | 3/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31115915 | 1.00 | EPHX2 (0.38) | EPHX2DDB1CRBNROCK2GRM4 | |
| SCHEMBL26435058 | 0.91 | ACHE (0.39) | EPHX2DDB1CRBN | |
| SCHEMBL26435948 | 0.91 | CRBN (0.38) | EPHX2DDB1CRBNFAAHMGLL | |
| SCHEMBL30407762 | 0.91 | CRBN (0.38) | EPHX2DDB1CRBNFAAHMGLL | |
| SCHEMBL26436052 | 0.90 | POLB (0.33) | POLBF11KLK1CCR3 | |
| SCHEMBL26435949 | 0.89 | FPR1 (0.36) | DDB1CRBNPOLBF11KLK1 | |
| SCHEMBL26435820 | 0.89 | F11 (0.35) | DDB1CRBNPOLBF11KLK1 | |
| SCHEMBL30407282 | 0.89 | F11 (0.35) | DDB1CRBNPOLBF11KLK1 | |
| SCHEMBL30408943 | 0.87 | EPHX2 (0.42) | EPHX2ROCK2GRM4MEN1MAPT | |
| SCHEMBL26435433 | 0.87 | EPHX2 (0.42) | EPHX2ROCK2GRM4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |