Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.45 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26436182 | 0.85 | KMT2A (0.48) | KDM4EGAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30828554 | 0.80 | KDM4E (0.61) | KDM4EGAAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL8506590 | 0.80 | ADH5 (0.60) | KDM4EGAAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL26436229 | 0.78 | NPC1 (0.51) | KDM4EGAAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL19334495 | 0.78 | HCAR3 (0.58) | KDM4EGAAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL28260920 | 0.77 | GAA (0.53) | KDM4EGAAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL13401515 | 0.77 | HCAR3 (0.77) | GAAMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1499437 | 0.76 | SMN1; SMN2 (0.48) | GAANPC1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL2427155 | 0.76 | JAK2 (0.47) | KDM4EGAAMAPTNPC1SMN1; SMN2 | |
| SCHEMBL1887153 | 0.76 | NAPRT (0.64) | KDM4EGAAMAPTNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | EZH2, BMI1, DOT1L | KDM4E 104/4885GAA 733/4885MAPT 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.