Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24003970 | 0.85 | KMT2A (0.55) | NPC1SMN1; SMN2RAB9AAURKAGAA | |
| SCHEMBL26436195 | 0.81 | RAB9A (0.58) | NPC1SMN1; SMN2RAB9AGAAKDM4E | |
| SCHEMBL26436207 | 0.78 | KDM4E (0.52) | NPC1SMN1; SMN2RAB9AAKR1C3AKR1C2 | |
| SCHEMBL26436230 | 0.78 | AURKA (0.55) | NPC1SMN1; SMN2RAB9AAURKAAKR1C3 | |
| SCHEMBL5925641 | 0.77 | MEN1 (0.54) | NPC1SMN1; SMN2RAB9AAURKAAKR1C3 | |
| SCHEMBL1887153 | 0.76 | NAPRT (0.64) | NPC1SMN1; SMN2RAB9AAURKAGAA | |
| SCHEMBL30828590 | 0.76 | POLB (0.62) | SMN1; SMN2GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL24003915 | 0.76 | KCNK3 (0.54) | SMN1; SMN2RAB9AKDM4EMAPT | |
| SCHEMBL1043517 | 0.74 | KDM4C (0.46) | NPC1RAB9AMAPTATMALDH1A1 | |
| SCHEMBL10144160 | 0.74 | PTGS2 (0.59) | NPC1RAB9AAURKAAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | EZH2, BMI1, DOT1L | NPC1 3716/4885SMN1; SMN2 11/4885RAB9A 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.