Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 4/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351867 | 0.83 | HDAC4 (0.47) | HDAC4HDAC1HDAC6HRH2HRH1 | |
| SCHEMBL12025753 | 0.83 | CTSK (0.46) | CTSKCTSSSCN9A | |
| SCHEMBL12025751 | 0.81 | ITGB3 (0.45) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL12025778 | 0.81 | ITGB3 (0.45) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL3054407 | 0.81 | SCN9A (0.64) | CTSKCTSSSCN9A | |
| SCHEMBL30832118 | 0.80 | HRH2 (0.53) | HDAC4HDAC1HDAC6HRH2HRH1 | |
| SCHEMBL5351866 | 0.79 | HDAC4 (0.51) | HDAC4HDAC1HDAC6HRH2HRH1 | |
| SCHEMBL21169918 | 0.77 | CTSS (0.52) | HRH2HRH1DRD2CTSKCTSS | |
| SCHEMBL25381677 | 0.76 | CTSS (0.56) | HDAC4HDAC1HDAC6CTSKCTSS | |
| SCHEMBL19066733 | 0.76 | CTSS (0.56) | HDAC4HDAC1HDAC6CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | EZH2, BMI1, DOT1L | HDAC4 237/4885HDAC1 38/4885HDAC6 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.