Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.64 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26436630 | 0.92 | CTSK (0.63) | CTSKCTSSHDAC4HDAC1REN | |
| SCHEMBL7446990 | 0.89 | CTSK (0.78) | CTSKCTSS | |
| SCHEMBL8083712 | 0.88 | CTSK (0.67) | CTSKCTSSHDAC4HDAC1REN | |
| SCHEMBL26436628 | 0.87 | CTSK (0.79) | CTSKCTSS | |
| SCHEMBL7439028 | 0.85 | CTSK (0.53) | CTSKCTSS | |
| SCHEMBL26436631 | 0.85 | CTSK (0.66) | CTSKCTSSREN | |
| SCHEMBL5212724 | 0.84 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL12203909 | 0.84 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL9608914 | 0.84 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL23454631 | 0.82 | HDAC4 (0.65) | CTSKCTSSHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | EZH2, BMI1, DOT1L | CTSK 4641/4885CTSS 4716/4885HDAC4 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.