Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.67 |
| ▸ | CTSS | P25774 | 4/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26436628 | 0.89 | CTSK (0.79) | CTSKCTSS | |
| SCHEMBL7367960 | 0.89 | CTSK (0.60) | CTSKCTSSHDAC4HDAC1REN | |
| SCHEMBL26436627 | 0.88 | CTSK (0.64) | CTSKCTSSHDAC4HDAC1REN | |
| SCHEMBL8088476 | 0.87 | CTSK (0.56) | CTSKCTSS | |
| SCHEMBL26436630 | 0.87 | CTSK (0.63) | CTSKCTSSHDAC4HDAC1REN | |
| SCHEMBL26436631 | 0.87 | CTSK (0.66) | CTSKCTSSREN | |
| SCHEMBL25492163 | 0.87 | NPSR1 (0.58) | CTSKCTSSHDAC4HDAC1 | |
| SCHEMBL22479132 | 0.84 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1REN | |
| SCHEMBL22527176 | 0.84 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1REN | |
| SCHEMBL23454631 | 0.84 | HDAC4 (0.65) | CTSKCTSSHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |