Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17106924 | 0.88 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL17106925 | 0.88 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL17106932 | 0.88 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL17106933 | 0.88 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL26436627 | 0.85 | CTSK (0.64) | CTSKCTSS | |
| SCHEMBL7442604 | 0.85 | CTSK (0.45) | CTSKCTSSMMP2MMP3 | |
| SCHEMBL7429952 | 0.85 | CTSK (0.45) | CTSKCTSSMMP2MMP3 | |
| SCHEMBL16462512 | 0.81 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL17106947 | 0.81 | CTSK (0.65) | CTSKCTSS | |
| SCHEMBL7443768 | 0.81 | CTSK (0.44) | CTSKCTSSGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |