SCHEMBL26437141 — predicted protein targets

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	NLRP3	Q96P20	8/20	0.59

▸	IL1B	P01584	7/20	0.37

▸	KDM4E	B2RXH2	2/20	0.35

▸	HSD17B10	Q99714	1/20	0.35

▸	ALDH1A1	P00352	2/20	0.34

▸	LMNA	P02545	1/20	0.34

▸	GAA	P10253	1/20	0.34

▸	HTT	P42858	1/20	0.34

▸	KMT2A	Q03164	1/20	0.34

▸	KAT2B	Q92831	1/20	0.33

▸	CCNT1	O60563	1/20	0.33

▸	CCNK	O75909	1/20	0.33

▸	CCNE1	P24864	1/20	0.33

▸	CDK2	P24941	1/20	0.33

▸	CDK9	P50750	1/20	0.33

▸	CDK12	Q9NYV4	1/20	0.33

▸	EGFR	P00533	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26437131	0.90	NLRP3 (0.47)	NLRP3IL1BKDM4EKAT2B
SCHEMBL26435307	0.88	NLRP3 (0.47)	NLRP3IL1BKDM4EHSD17B10ALDH1A1
SCHEMBL26437590	0.88	NLRP3 (0.45)	NLRP3IL1BKAT2B
SCHEMBL26436526	0.88	NLRP3 (0.56)	NLRP3IL1B
SCHEMBL26435057	0.87	NLRP3 (0.49)	NLRP3IL1BKDM4EHSD17B10ALDH1A1
SCHEMBL26437140	0.85	NLRP3 (0.51)	NLRP3IL1BKDM4EHSD17B10ALDH1A1
SCHEMBL30214821	0.84	NLRP3 (0.81)	NLRP3IL1BKAT2BCCNT1CCNK
SCHEMBL29275831	0.84	NLRP3 (0.81)	NLRP3IL1BKAT2BCCNT1CCNK
SCHEMBL29276147	0.84	NLRP3 (0.81)	NLRP3IL1BKAT2BCCNT1CCNK
SCHEMBL26437259	0.83	NLRP3 (0.40)	NLRP3IL1BKAT2BCCNKCDK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023066377-A1	NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF	索智生物科技（浙江）有限公司	2023-04-27	—	—	WO	disclosed