Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 12/20 | 0.40 |
| ▸ | IL1B | P01584 | 6/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437284 | 0.91 | NLRP3 (0.49) | NLRP3IL1BCCNKCDK7CCNH | |
| SCHEMBL26437245 | 0.87 | IL1B (0.43) | NLRP3IL1BCCNKCDK7CCNH | |
| SCHEMBL26434556 | 0.87 | IL1B (0.50) | NLRP3IL1B | |
| SCHEMBL26437590 | 0.86 | NLRP3 (0.45) | NLRP3IL1BKAT2B | |
| SCHEMBL26437409 | 0.85 | IL1B (0.52) | NLRP3IL1B | |
| SCHEMBL26437255 | 0.84 | IL1B (0.49) | NLRP3IL1B | |
| SCHEMBL26437249 | 0.84 | NLRP3 (0.55) | NLRP3IL1BCCNKCDK12 | |
| SCHEMBL26437141 | 0.83 | NLRP3 (0.59) | NLRP3IL1BCCNKCDK12KAT2B | |
| SCHEMBL26434562 | 0.81 | NLRP3 (0.45) | NLRP3IL1B | |
| SCHEMBL26434560 | 0.79 | IL1B (0.41) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |