Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437234 | 0.88 | LMNA (0.54) | LMNAL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15328300 | 0.81 | CYP3A4 (0.53) | LMNAL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL26437251 | 0.81 | CA12 (0.44) | LMNAL3MBTL1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21591042 | 0.81 | MTNR1A (0.36) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL26437235 | 0.80 | NR1H2 (0.56) | LMNAL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL18786715 | 0.77 | LMNA (0.47) | LMNAL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25386161 | 0.77 | LCK (0.49) | LMNAL3MBTL1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL25329460 | 0.75 | NR1I2 (0.42) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27452329 | 0.75 | NQO2 (0.38) | LMNAALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL21593357 | 0.74 | PTGS2 (0.42) | LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066204-A1 | SIK INHIBITOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2023-04-27 | — | — | WO | disclosed |