Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 13/20 | 0.41 |
| ▸ | TNF | P01375 | 5/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26092916 | 0.91 | IL1B (0.49) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL30375424 | 0.91 | IL1B (0.49) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL26437272 | 0.85 | NLRP3 (0.41) | NLRP3 | |
| SCHEMBL26133269 | 0.85 | IL1B (0.52) | IL1BTNFNLRP3KCNH2METAP1 | |
| SCHEMBL30375286 | 0.85 | IL1B (0.52) | IL1BTNFNLRP3KCNH2METAP1 | |
| SCHEMBL26438433 | 0.85 | IL1B (0.52) | IL1BTNFNLRP3KCNH2METAP1 | |
| SCHEMBL24695701 | 0.83 | NLRP3 (0.54) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL26434286 | 0.83 | IL1B (0.49) | IL1BTNF | |
| SCHEMBL26437254 | 0.83 | MKNK1 (0.34) | IL1BTNFNLRP3 | |
| SCHEMBL26437566 | 0.82 | IL1B (0.48) | IL1BTNFNLRP3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |